MICRO BI
High quality rotary filling system

In essence, this integrated filling and isolation system offers a comprehensive solution for sterile liquid production. It merges cutting-edge rotary filling system with a superior aseptic environment, paving the way for efficient, reliable, and contamination-free production cycles.

MICRO BI is the perfect solution for achieving a streamlined and adaptable fill-finish process that prioritizes quality and efficiency.

Filling line main features

This unit offers a minimized starwheel in tandem with dialed in servo control and flexibility. Trayed vials and/or nested vials/syringes/cartridges are introduced for fill finish. Vials are weighed/filled and closed (stoppers and optional caps.) 2 up filling alternatives give the user a range of outputs and flexibility. The pre-designed units can be set up both “isolator ready” and open RABS configurations.

Full Servo design incorporates filling precision and repeatability, product conservation and closing systems with great process windows. The SP internal core competencies include excellent glass handling/fluid dynamics skill sets and automation practice. The machinery is very friendly for cleanability and ISO 5 air flow practice. Easy changeovers and easy touch screen interface; Modern Documentation and validation support.

Base Unit Equipmen

• 1 or 2 Filling Pumps fully integrated with IDT scale algorithm with auto feedback to peristaltic pumps. Piston pumps available upon request
• One size part set for each type of closure with base machine (up to 2)
• Central machine starwheel performs all functions – filling and closing and optional items.
• Baseline Keba controls for motion control/AB or Siemens PLC optional, PC based touch panel screen.

Isolator main features

• Filtration grade with H14 filters IN / OUT
• Exhaust fans positioned in the technical area
• Automatic Shutter gates, for IN / OUT for differential pressure & containment control
• LED lighting, positioned on the outside of the aseptic process area
• Doors with 12 mm thick tempered glass with inflatable gaskets
• Glove ports with independent safety barrier
• Integrated Glove Integrity Tester with Speedy Glove
• Return ducts for optimal uniformity of the air flow
• Bag-In Bag-Out filtration upon request
• Isolator walls made of 3 mm thick stainless steel AISI 316L with internal finish Mirror Brite < 0.3μm and round corners of 20 mm radius
• Spray Balls and Spray guns for facilitating the cleaning of the unit at the end of the production
• Integrated Comecer VPHP generator for automatic decontamination of the equipment
• Isolator & filling machine together will satisfy the containment level Class 3, ISO 10648-02. Leak rate < 1%