Nestlé Baby milk manufacturing inside an aseptic isolator

A case study of Comecer Pharma solutions

Isolator_NESTLE_Swisse_working_box

Customer Challenge

Manufacture trial batches of baby milk under aseptic condition within an isolator, with complete process and equipment integration:  sterile transfer from fermentation, centrifugation, separation, mixing and can filling

Performance Requirements

  • Sterile transfer from fermenter, positioned outside isolator, to inside isolator
  • Centrifuge for 1 liter bottles
  • Separation with peristaltic pump and mixing with magnetic stirrer
  • Can filling with peristaltic pump and can closing system
  • Sterile environment inside the isolator

Solution Highlights

Comecer Process Engineering studied, designed and manufactured an isolator with complete process integration, including a special centrifuge, and can filling/closing system

  • Complete custom aseptic multi-chamber isolator (5 meters long, with 2 chambers and transfer chamber): centrifugation, separation, can filling/closing and outlet chamber
  • Complete custom fitting with internal solutions for tools and ancillaries arrangement
  • Laminar air flow in all chambers
  • Special centrifuge for 1 liter bottles with unique isolator integration
  • Separation system and can filling with integrated special peristaltic pump
  • Can closing system with complete integration
  • Integrated bio-decontamination systems using the purest hydrogen peroxide solution to achieve a 6log decrease in contamination

Location: Konolfingen

Category: Pharma

Installed machines: Baby milk manufacturing inside an aseptic isolator

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