Updated guide to ALCEO resources

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Solid Target technology is receiving much interest lately. Here is an updated list of all valid resources that reference our ALCEO Solid Target Processing System.

Product information

• Technical Datasheet: ALCEO Solid Target Processing System
• ALCEO Version 2.0 details: New Improvements for ALCEO Solid Target Technology

Posters

• SNMMI Vancouver 2022: Fully automated, commercial cassette-based production of high-purity [64Cu]CuCl2 from solid Ni target
• ISRS 2019: Automated production of Cu-64, Zr-89, Ga-68, Ti-45, I-123, and I-124 with a medical cyclotron, using a solid target commercial system
• ISRS 2019: Automated production of Ga-68 chloride and Ga-68-Dotatate on a low-energy medical cyclotron
• ISRS 2017: Improved production of I-124 with the Comecer ALCEO Halogen System for routine use
• EANM 2017: Radiometals production by only one solid target system

Studies

• Elsevier Applied Radiation and Isotopes, October 2018 issue: Improved small-scale production of iodine-124 for radiolabeling and clinical applications
• PubMed, June 2018: Fully Automated Production and Characterization of 64Cu and Proof-of-Principle Small-Animal PET Imaging Using 64Cu-Labelled CA XII Targeting 6A10 Fab (Note: the article mentions the ALCEO Solid Target System. Our R&D department is committed to the constant improvement of isotope production chemistry. That’s why we developed ALCEO 2.0 and 3.0, while the article references ALCEO 1.0)
• European Journal of Medical Physics, May 2016 issue: GEANT4 simulation of cyclotron radioisotope production in a solid target
• Applied Radiation and Isotopes Journal, Jan 2016 issue: Semi-automated production of 89Zr-oxalate/89Zr-chloride and the potential of 89Zr-chloride in radiopharmaceutical compounding

Presentations

• Terachem 2018: Automated production of Cu-64, Zr-89, Ga-68, Ti-45, I-123 and I-124 with a medical cyclotron, using a commercial solid target system.
• SNMMI 2018 Annual Meeting: 68Ga and 45Ti production on a GE PETtrace cyclotron using the ALCEO solid target 
• SNMMI 2018 Mid-Winter Meeting: Synthesis of radiometals from solid targets used for radiolabeling
• WTTC 2016 (by third-party): Automation of 89Zr production using a Comecer Taddeo synthesizer (Note: it references ALCEO 1.0, so it talks about a process which is not completely automated because ALCEO 1.0 can make a totally automatic mode only 64Cu and not 89Zr)