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ValueCell FLEXY
Stand alone Cell & Gene Therapy isolator with Flexycult integration

ValueCell FLEXY is the new flexible and multi-tasking isolator for cell & gene therapy.

The configuration has been designed for Cell &Gene Therapy applications requiring high throughput, modularity and expansion capabilities.

We all know, in a Cell&Gene application, the incubation capacity is often the bottleneck being the incubation steps much more time demanding than the processing phases. In lack of additional incubation possibilities, you could run out of your production capacity, definitely compromising your targets, despite you could still have processing space and time.

COMECER can offer you the solution: integrate the system with an interface to connect with FlexyCult, an external incubation system.

Cell Culture Isolators and Flexycult Incubation System for Advanced Therapy Labs – Co.don AG Project video


  • Laminar airflow
  • Fully PLC controlled
  • Software GAMP 5 compliant (21CFR Part 11 available upon request)
  • Friendly operator interface (HMI)
  • Integrated decontamination system (Vapor Phase Hydrogen Peroxide)
  • High grade stainless steel AISI 316L internally and AISI 304 externally
  • Fully welded chamber with 20 mm radius
  • Illuminate™ MI: IIoT manufacturing intelligence platform and factory-floor management

The combinations of different modules can be various. In the example shown an isolator with two different processing areas, is sharing a common zone of accessories used for product in and out. In this isolator operators are running different processes in parallel sessions, with coordinated use of the common area and a unique decontamination system. The solution is saving space and the use of two complete solutions.

Basically, all the COMECER isolators can be adapted to be used in the FLEXY configuration. The FLEXY configuration can be obtained by integrating the FLEXY interface (to be used with the FlexyCult incubation system or as a standard RTP with suitable accessories) and the suitable track to allow incubator to slide towards the connection position.

Cell & gene therapy isolator with Flexycult integration

ValueCell FLEXY isolator is specially conceived for use with FlexyCult™, for handling cell cultures in a certified Grade A environment.

The modular cell culture isolator can be connected to FlexyCult™ incubators via sealed RTP connections, allowing the incubators to be opened in
an aseptic environment. Inside the isolator are the standard laboratory instruments for analysing and handling cell cultures: it includes centrifuges, refrigerators, a culture oven, and sampling access.

The isolator essentially comprises three chambers with positive pressure relative to the laboratory. These are:

  • 1 pre-chamber for the introduction of materials.
  • 2 main chambers for handling cell cultures.

The isolator is equipped with a VPHP generator for the decontamination of the work areas.

+ illuminate

Release the full potential of ValueCell FLEXY with Illuminate™ Manufacturing Intelligence

Use real-time machine performance data to pinpoint where to focus efforts to reduce downtime, maximize line throughput, improve product quality, and make sustainable production improvements. Learn more »

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ATMP_FlexyCult cell incubation system


Incubation System for Advanced Therapy Labs

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