Updated guide to ALCEO resources

Solid Target technology is receiving much interest lately. Here is an updated list of all valid resources that reference our ALCEO Solid Target Processing System.

Product information

• Technical Datasheet: ALCEO Solid Target Processing System
• ALCEO Version 2.0 details: New Improvements for ALCEO Solid Target Technology

Posters

• SNMMI Vancouver 2022: Fully automated, commercial cassette-based production of high-purity [64Cu]CuCl2 from solid Ni target
• ISRS 2019: Automated production of Cu-64, Zr-89, Ga-68, Ti-45, I-123, and I-124 with a medical cyclotron, using a solid target commercial system
• ISRS 2019: Automated production of Ga-68 chloride and Ga-68-Dotatate on a low-energy medical cyclotron
• ISRS 2017: Improved production of I-124 with the Comecer ALCEO Halogen System for routine use
• EANM 2017: Radiometals production by only one solid target system

Studies

• Elsevier Applied Radiation and Isotopes, October 2018 issue: Improved small-scale production of iodine-124 for radiolabeling and clinical applications
• PubMed, June 2018: Fully Automated Production and Characterization of 64Cu and Proof-of-Principle Small-Animal PET Imaging Using 64Cu-Labelled CA XII Targeting 6A10 Fab (Note: the article mentions the ALCEO Solid Target System. Our R&D department is committed to the constant improvement of isotope production chemistry. That’s why we developed ALCEO 2.0 and 3.0, while the article references ALCEO 1.0)
• European Journal of Medical Physics, May 2016 issue: GEANT4 simulation of cyclotron radioisotope production in a solid target
• Applied Radiation and Isotopes Journal, Jan 2016 issue: Semi-automated production of 89Zr-oxalate/89Zr-chloride and the potential of 89Zr-chloride in radiopharmaceutical compounding

Presentations

• Terachem 2018: Automated production of Cu-64, Zr-89, Ga-68, Ti-45, I-123 and I-124 with a medical cyclotron, using a commercial solid target system.
• SNMMI 2018 Annual Meeting: 68Ga and 45Ti production on a GE PETtrace cyclotron using the ALCEO solid target 
• SNMMI 2018 Mid-Winter Meeting: Synthesis of radiometals from solid targets used for radiolabeling
• WTTC 2016 (by third-party): Automation of 89Zr production using a Comecer Taddeo synthesizer (Note: it references ALCEO 1.0, so it talks about a process which is not completely automated because ALCEO 1.0 can make a totally automatic mode only 64Cu and not 89Zr)