The series is a family of configurable machines based on various parameters such as:
The radioisotopes that can be produced are 64Cu, 89Zr, 124I, 123I and 68Ga.
The complete ALCEO configurations (ALCEO FULL) feature a single PTS (pneumatic transfer system) and Cooling System unit: the transport of the target to the corresponding module is performed via a target switch.
The radionuclides produced are available in a form suitable for radiopharmaceutical synthesis.
The integrated system allows all the operations to be carried out without the manual intervention of operators.
The ALCEO system is designed for the application of commercial cyclotrons with energy ranging between 5 and 30 Mev.
It allows the irradiation of a Tellurium oxide deposit 124Te and 123Te to obtain the equivalent radionuclide 124I and 123I.
It consists of a module for the production of 124I and 123I (mixed process) and one single PTS.
The target is the component which is directly irradiated by the cyclotron beam: it is an enriched metal isotope (123Te and 124Te) which produces the positron emitter (123I and 124I) after the bombardment.
The irradiation unit is directly connected to the cyclotron and guarantees the correct positioning of the target in front of the beam port. Target positioning is fully automated. The unit is connected to its own “water and helium cooling system”. The cooling system is connected to the cyclotron cold water and helium circuit, as a normal liquid target.
The unit can be placed inside a hot cell and must be connected to the PTS unit with the target transfer tube. The EVP module contains the necessary components for the following operations:
The purification task makes use of a “disposable cassette”, in order to avoid the module contamination. Comecer supplies the cassette, while the preparation of the required synthesis reagents is the customer’s responsibility.
It consists of one single PTS and two modules (a Dissolution/Transfer unit and a Purification unit) for the production of metal radioisotopes. The Dissolution/Transfer unit can be provided with several accessories such as the setup for Ni Plating and Cu Dissolution; Zn Plating and Ga Dissolution, Zr Dissolution. The modular configuration allows the simple upgrade for the production of the other metal radioisotopes (64Cu, 89Zr, 68Ga). In the fully accessorised configuration, it allows the irradiation of:
The Alceo Metal target shuttle allows the automatic positioning of the metal isotope in front of the cyclotron beam.
The irradiation unit is directly connected to the cyclotron and guarantees the correct positioning of the target in front of the beam port. Target positioning is fully automated. The unit is connected to its own “water and helium cooling system”.
It can be placed inside a hot cell which is connected to the cyclotron by a flexible tube for the target transfer. It is a pneumatic system that automatically carries out the following operations:
It can be placed inside a hot cell and must be connected to the Dissolution/Transfer unit by capillary lines. The Purification module contains the necessary components for the purification by ion chromatography of the produced radioisotope (64Cu, 89Zr, 68Ga). The module is based on disposable cassettes.
ALCEO METAL RETROFIT is the best solution for a pre-existing laboratory, where hot cells and trenches for capillary passage do not possess the requirements for proper installation of the ALCEO METAL.
ALCEO METAL RETROFIT is based on ‘accessories’ as the standard Alceo Metal, but the dissolution and purification phases are separated in distinct areas. In this configuration, connection between the two areas consists of a single fluid transfer capillary and not of a complex pneumatic transfer system of the target using corrugated pipe. In the fully accessorised configuration, it allows the production of 64Cu, 89Zr, 68Ga.