PHL Series Sterile Isolator for Cellular Labeling

The Cellular Labeling in Nuclear Medicine are classified by Good Radiopharmacy Practice Standards in the Preparation of Radiopharmaceuticals in Nuclear Medicine as “extemporaneous preparations” and must be carried out in a laminar flow hood (Class A) located in a Class B environment, or within an isolator, which can maintain sterility, located in a Class D environment.

The second solution avoids having to set up a cleanroom within the Nuclear Medicine Department and guarantees full protection of the product and operator.
The labeling operations are carried out inside the box, thanks to a pair of gloves found on the main wall. The material passes through the pre-chamber (in Class B) for the main chamber to never be in direct communication with the external environment.

PHL - Sterile Isolator for Cellular Labeling


  • Modular design and flexible configuration
  • 7” touch-screen operator panel to check and trace the critical parameters of the machine both in “at rest” or “in operation” mode.
  • DOP test connections (filter leakage test).

The handling environment, just like the pre-chamber, is in negative pressure with respect to the external environment, thereby ensuring compliance with the Radiation Protection Standards.
All the operations, normally performed within an area in the Nuclear Medicine Department intended for cellular markings, are summarised inside the isolator.
All the production phases can be monitored closely with maximum protection through the large windows.
The cleaning operations at the end of the cycle can be performed with the gloves, whereas the front wall of the work chamber can be opened completely in order to facilitate maintenance operations.

The isolator is mounted on wheels, which facilitates the maintenance and cleaning operations.
Materials can be sanitised and entered in the work box through the inlet pre-chamber.
The pre-chamber has a manually-opened front tempered glass door with a closing sensor and tightness system with inflatable gaskets made of pharmaceutical grade FDA-approved silicone.
A second door, equipped with the same tightness system, connects the pre-chamber with the work chamber.

Both doors have an interlock that does not allow them to be opened simultaneously. This safety device prevents the work chamber from being connected directly with the external environment, thereby guaranteeing sterility within.
A tray mounted on sliding guides is set inside the pre-chamber to facilitate the transferring of materials to the work chamber.
The inner part of the work chamber is large enough to allow the handling operations and fractioning of cytostatic drugs, while in a seated position and using gloved flanges. An electric socket can be found on the rear part.

The front wall can be opened completely and is equipped with an opening handle, gas springs to balance the weight and perimeter inflatable gaskets made of pharmaceutical grade FDA-approved silicone. The wall can be tilted 6° in order to have a better view of within.
The software regulates a number of interlocks, which prevents a number of doors being opened simultaneously.

2 oval glove flanges are found on the wall equipped with ambidextrous gloves (the type of material and glove size will be defined according to the customer requirements): they have a double groove for safe replacement (the glove can be replaced without connecting the chamber to the outside).

Related products

TIMO 2 – Syringe Dispensing System

TIMO 2 is a semi-automatic dispensing system that makes use of components and software developed and adopted by...
Learn more

BH Series – Biohazard Class A Hood

The BH SERIES microbiological safety hood, also known as laminar flow workbench, has been designed to work specifically...
Learn more

ELIZA Series – Shielded Laminar Flow Isolator

ELIZA is a shielded laminar flow isolator suitable for handling, dispensing and calibrating beta/gamma-emitting radiopharmaceuticals, in accordance with...
Learn more

LETHO – Automatic Compact Radiopharmaceutical Injector

Letho is a compact radiopharmaceutical injector system for the automatic intravenous infusion of radio drugs or radio tracers....
Learn more

Sign up for your Comecer Account

Registration is for professionals that work with containment and Isolation Technologies and grants full access to our product data sheets and catalogues.
I read and understood the information sheet pursuant to Art. 13 GDPR
I express my consent to process my personal data for marketing purposes and the sending of promotional and informative material, believe useful, by the sending of newsletter and commercial communications concerning Comecer products/services, as indicated in the section “Data processed and Purposes of processing” of the Privacy Policy published on the website.
I express my consent also for the processing of my personal data for profiling purposes and for the analysis of the preferences, interests and habits, as indicated in the section “Data processed and Purposes of processing” of the Privacy Policy published on the website.

Maggiori informazioni



Warning! The content in this page is available only in the following languages: Italian

I cookie necessari sono i cookie tecnici cioè quelli il cui utilizzo non richiede il consenso dell’utente.

Questi cookie sono essenziali per consentire di navigare in un sito web e utilizzarne tutte le funzionalità. Senza questi cookie, che sono assolutamente necessari, un sito web non potrebbe fornire alcuni servizi o funzioni e la navigazione non sarebbe agevole e facile come dovrebbe essere. Un cookie di questo tipo viene inoltre utilizzato per memorizzare la decisione di un utente sull’utilizzo di cookie sul sito web.

I cookie tecnici sono essenziali e non possono essere disabilitati utilizzando questa funzionalità.
In generale comunque i cookie possono essere disattivati completamente nel proprio browser in qualsiasi istante.



Warning! The content in this page is available only in the following languages: Italian

I cookie statistici vengono utilizzati per monitorare le performances del sito, per esempio per conoscere il numero di pagine visitate o il numero di utenti che hanno visualizzato una determinata sezione.

I cookie statistici utilizzati dal nostro sito si avvalgono di servizio di Google Analytics.

L’analisi di questi cookie genera dati statistici anonimi e aggregati senza riferimento alcuno all’identità dei navigatori del sito. Sono utili anche per valutare eventuali modifiche e miglioramenti da apportare al sito stesso.



Warning! The content in this page is available only in the following languages: Italian

I cookie di targeting sono cookie impostati da terze parti come YouTube, Facebook, Twitter.

Questi cookie tengono traccia del tuo comportamento come la riproduzione di video o quali tweet hai già visualizzato.

Se non viene dato il consenso a questi cookie, non sarà possibile guardare i video su questo sito web o utilizzare la funzionalità di condivisione sui social.

Questi cookie possono essere utilizzati dal fornitore di cookie per creare un profilo dei tuoi interessi e mostrarti pubblicità pertinenti su altri siti. Non memorizzano direttamente informazioni personali, ma si basano sull'identificazione univoca del browser e del dispositivo Internet.