MANUELA Shielded Laminar Flow Isolator for Nuclear Medicine

MANUELA is a shielded cell for the manipulation of radio medicines, in particular, for the fractioning of positron emitting isotopes.

Used in Radiopharma Production Nuclear Medicine For R&D Radiochemistry and Radiopharma Synthesis Filling Dispensing Dose Calibration


  • Modular design and flexible configuration
  • Touch screen for hot cell and dispensing system
  • Airtight connections for radioactive fluids
  • Fluid supply lines made of AISI 316L stainless steel with ball shut-off valves
  • DOP test connections (filter leakage test)
  • Dose calibrator (available in the versions 2 Ci or 20 Ci) with touch screen console
  • Set-up for the Geiger probes for measurement of the radioactivity present inside the cell

The machine offers exclusive technical solutions which guarantee unique performance in terms of:

  • Sterility: the laminar air flow work area (Class A according to EEC-cGMP) allows handling radiopharmaceuticals in absolute safe conditions for the product
  • Radioprotection: for the accuracy and completeness of the shieldings, the concentration of the operations in a single closed environment, the decontamination of all the work surfaces
  • Ergonomics: all the components required for the dose preparation are placed within the range of action of the operator’s hands
  • Safety: the work environment  in negative pressure guarantees the best protection to the operator, the inner laminar flow is located in the front area of the box and it ensures the best protection to the radio medicine
  • Management of the critical parametres: the isolator is equipped with a modern operator panel to control, adjust and export the cell inner parametres, notifications and alarms
  • Versatility: the large internal chamber and the shape of the work surface allow installing automatic synthesis modules or fractionators for syringes and vials
  • Duration through time: the high-quality of the components used ensures duration over time and performance consistency.

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