TABLETOP DISPENSING SYSTEM
Tabletop filling and closing module for injectable vials

COMECER - Tabletop Dispensing Solution for Injectable Vials

Introducing TABLETOP, Comecer’s compact solution for filling and closing of injectable vials in R&D, clinical and advanced therapy environments.

Imagine a standalone module that, once prepared, enables automatic dispensing and closing and can be installed inside a Class A containment isolator with laminar flow to replicate sterile liquid production needs on a reduced footprint. The new TABLETOP DISPENSING SYSTEM is that solution.

Designed for lyo or liquid vials, it is ideal for clinical trials, R&D, ATMP and Cell & Gene production plants, delivering flexible configuration, clean design and in‑line process control.

See TABLETOP DISPENSING SYSTEM in action

Tabletop Dispensing Solution for Injectable Vials | Comecer

  • Aseptic-ready integration: suitable to install inside an aseptic isolator with laminar flow throughout the process.
  • Peristaltic pump dosing for reliable and gentle dispensing.
  • Disposable fluid path option: filling circuit can be integrated with a full disposable circuit to support contamination-control strategies.
  • One module, multiple operations: unique module for filling, stoppering and sealing.
  • Lyo stoppering capability: configurable to perform filling and lyo stoppering.
  • Stand‑alone crimping mode available via recipe settings.
  • High accuracy control: optional gravimetric accurate filling and 100% check weighing through integrated load cell.
  • Format and closure flexibility: supports pre‑stoppered vials and a specific configuration for push‑fit caps.
  • Clean, compact design engineered to avoid critical airflow disruption and simplify operator preparation.

TABLETOP DISPENSING SYSTEM Features

Filling & Closing Module

The TABLETOP module is a standalone unit designed to manage filling and closing operations with semi‑automatic handling and automatic cycles once prepared. It supports liquid filling and lyophilization stoppering, with flexible recipe-based configuration.

TABLETOP DISPENSING SYSTEM - Components

 

Core components and functions include:

  • Peristaltic pump dosing system
  • Pneumatic vial transfer grippers
  • Mechanical alu-seal crimping
  • Sensor checks for stopper and seal presence on grippers
  • Load cell for dosing control and push‑fit vertical force monitoring

In‑Line Weighing & Accuracy

TABLETOP can be configured for gravimetric filling where high precision is required, and integrates 100% weigh check to support batch consistency.

Closure Handling Configuration

The system can be configurated for different closure types, including lyo stoppers, serum stoppers, alu-seals (flip-off/tier-off) and optional push‑fit caps, with support for pre‑stoppered vials.

Integration in an Aseptic Isolator

The TABLETOP solution is designed to be installed inside a Class A containment isolator with laminar flow, replicating sterile production requirements. A complete Comecer package can include isolator chamber, air filtration/ventilation, and VPHP decontamination systems.

Safety and Control with TABLETOP: Built for aseptic workflows

Aseptic processing demands repeatability, cleanliness and control. TABLETOP supports these needs through:

  • Clean design engineered to minimize airflow disruption in isolator environments.
  • Reduced manual risk thanks to automatic dispensing and closing cycles once the module is prepared.
  • In-line control via integrated load cell for 100% check weighing (and optional high-precision gravimetric filling).
  • Regulatory readiness: designed in line with GMP expectations and available with Annex 11 / 21 CFR Part 11 and CE/UL references in the technical framework.

Working Range & Alternative Configurations

Standard working range (typical):

  • Vial diameter 22 – 36 mm, height 45 – 65 mm
  • Stopper 20 mm serum type
  • Alu-seal 20 mm tear-off

Alternative formats available, including:

  • Vials up to Ø 55 mm and height up to 75 mm (depending on configuration)
  • Stoppers 13 mm (serum/lyo) and 20 mm (lyo)
  • Alu-seals 13/20 mm (flip-off/tier-off), push-fit caps 13/20 mm

Frequently Asked Questions

Can TABLETOP be used for both liquid and lyo processes?
Yes. The module is suitable for Lyo or Liquid vials and can be configured for filling and lyo stoppering.

Does the solution support 100% in-line control?
Yes. It features in-line process control through an integrated load cell enabling 100% check weighing.

Is there an option for disposable fluid paths?
Yes. The filling circuit can be integrated with a full disposable circuit.

Can it manage pre-stoppered vials or push-fit caps?
Yes. The system supports pre‑stoppered vials and includes a dedicated configuration for push‑fit caps with force monitoring.

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